Dwight A. Bellinger, DVM, PhD. Professor, School of Medicine, University of North Carolina—Chapel Hill. Dr. Bellinger is the Interim Director of the Division of Laboratory Medicine at UNC. He has 23 years of experience in clinical veterinary practice, and during that time has trained students from a variety of backgrounds and with a range of experience levels. He will contribute several modeules in this course, including the ehtics of animal experimentation, principles of animal surgery, adn the dog and pig models maintained by the University

Kim L. R. Brouwer, PharmD, PhD. Professor and Chair of the Division of Pharmacotherapy and Experimental Therapeutics, School of Pharmacy, University of North Carolina—Chapel Hill. Dr. Brouwer's expertise is in the area of pharmacokinetics, with particular emphasis on animal models of hepatobiliary drug disposition (active uptake, biliary excretion and hepatic metabolism). She has maintained a strong translational research program at UNC and her research group routinely integrates mechanistic information obtained in cellular models into descriptions of the intact organ, whole animals and human.

Virginia L. Godfrey, DVM, PhD. Professor, School of Medicine, University of North Carolina—Chapel Hill. Dr. Godfrey has considerable expertise in the management of large-scale rodent colonies, having directed the program at the Biology Division, Oak Ridge National Laboratory for 8 years. This large genetics research program had a daily census of over 200,000 animals and over 1,000 mouse strains. She is board-certified in Veterinary Anatomic Pathology and has 17 years experience with the breeding, maintenance, and phenotypic assessment of laboratory rodents. She currently oversees the Division of Laboratory Animal Medicine's Health Surveillance program, including supervision of in-house microbiology and necropsy services.

Rhonda Lewallen. IACUC Training/Compliance Coordinator, University of North Carolina— Chapel Hill. Ms. Lewallen has created the current IACUC training program at UNC and will provide instruction in animal handling and principles of small animal surgery.

Kathleen Mohr. Mutant Mouse Regional Resource Center Facility Manager, University of North Carolina— Chapel Hill. Ms. Mohr is the Facility Manager of the Mutant Mouse Regional Resource Center at UNC, one of four centers in the nation funded by NCRR/NIH. She oversees and trains all personnel in cryopreservation, embryo transplant survery, in vitro fertilziation, mouse sperm phenotyping, and breeding colongy management. She has served as organizer and lead instructor for 6 years for the Carolina Workship on Genetic Engineering of Mice, teaching pronuclear and blastocyst microinjection, surgical procedures, colony management, embryo isolations and injection needle fabrication.

Adam M. Persky, PhD. Clinical Assistant Professor, School of Pharmacy, University of North Carolina—Chapel Hill. Dr. Persky handles the course scheduling and preparation, develop course materials, coordnate student registration and assist in the course evaluation. His primary responsibility in the School of Pharmacy is the development and delivery of advanced external coursework. He has expertise in pharmacokinetics and is well versed in the theory and application of microdialysis.

Gary M. Pollack, PhD. Professor and Executive Associate Dean, School of Pharmacy, University of North Carolina— Chapel Hill. Dr. Pollack's expertise is in the area of theoretical and applied pharmacokinetics and pharmacodynamics, with particular emphasis on animal models of CNS drug disposition and action. His laboratory has a long standing history using many of the intact animal, perfused organ, and mathematical modeling technqiues included in the short course.

David R. Taft, PhD. Associate Professor, School of Pharmacy, Long Island University. Dr. Taft is a former post-doctoral fellow from UNC and is recognized for his expertise in the pharmacokinetics of renal excretion and the use of animal and organ models to explore mechanism and kinetics of renal clearance. He will provide lecture material and laboratory demonstrations on the isolate perfused rat kidney model.

Janice D. Wagner, DVM, PhD. Associate Professor of Pathology and Assistant Director of the Animal Resource Center, Wake Forest University. Dr. Wagner has a long and distinguished track record in the utilization of primate models of human disease and will teach the primate module of the course