Robert Blouin

Home > Faculty & Research > Faculty Directory
Document Actions

Publications

1. Westerfield BT, Blouin RA:  Ethchlorvynol intoxication.  South Med J. 70:1019-1020, 1977.

2. Bivens BA, Rapp RP, Griffen WO Jr., Blouin RA, Bustrack JA:  Dopamine - phenytoin interaction.  Arch Surg 113:245-249, 1978.

3. Rapp RP, Bustrack JA, Blouin RA:  Dopamine interaction.  Drug Intell Clin Pharm 12:249, 1978.

4. Blouin RA, Mann HJ, Griffen WO Jr., Bauer LA, Record KE:  Tobramycin pharmacokinetics in morbidly obese patients.  Clin Pharmacol Ther 26:508-512, 1979.

5. Bauer LA, Blouin RA, Griffen WO Jr., Record KE, Bell RM:  Amikacin pharmacokinetics in morbidly obese patients.  Am J Hosp Pharm 37:519-522, 1980.

6. Blouin RA, Bauer LA, Piecoro JJ, Holland NH:  Decreased gentamicin half-life during peritoneal dialysis:  A case report.  Drug Intell Clin Pharm 14:218-219, 1980.

7. Blouin RA, Bauer LA, Bustrack JA, Record KE, Bivens BA:  Theophylline hemodialysis clearance.  Ther Drug Monit 2:221-223, 1980.

8. Blouin RA, Elgert JF, Bauer LA:  Theophylline clearance:  effect of marked obesity.  Clin Pharmacol Ther 28:619-623, 1980.

9. Blouin RA, Erwin WG, Dutro MP, Bustrack JA, Rowse KL:  Chloramphenicol hemodialysis clearance. Ther Drug Monitor 2:351-354, 1980.

10. Oeltgen PR, Hamann SR, Blouin RA:  Comparison of gentamicin assays.  Ther Drug Monit 2:423-425, 1980.

11. Bauer LA, Blouin RA:  Influence of age on theophylline clearance in patients with chronic obstructive pulmonary disease.  Clin Pharmacokinet 6:469-474, 1981.

12. Dionne RE, Bauer LA, Gibson GA, Griffen WO Jr., Blouin RA:  Estimating creatinine clearance in morbidly obese patients.  Am J Hosp Pharm 38:841-844, 1981.

13. Lawson LA, Blouin RA, Smith RB, Rapp RP, Young AB:  Phenytoin-dexamethazone interaction: a previously unreported observation.  Surg Neurol 16:23-24, 1981.

14. Bailey RT, Young AB, Rapp RP, Blouin RA:  Theophylline toxicity after the use of aminophylline in the treatment of cerebral vasospasm.  Neurosurgery 9:722-724, 1981.

15. Bauer LA, Blouin RA:  Influence of age on tobramycin pharmacokinetics in patients with normal renal function.  Antimicrob Agents Chemother 20:587-589, 1981.

16. Bauer LA, Bauer SP, Blouin RA:  The effect of acute and chronic renal failure on theophylline clearance.  J Clin Pharmacol 22:65-68, 1982.

17. Lawson LA, Blouin RA, Parker PF:  Quality assurance program for a clinical pharmacokinetic service.  Am J Hosp Pharm 39:607-609, 1982.

18. Blouin RA, Bauer LA, Miller DD, Record KE, Griffen WO Jr.,:  Vancomycin pharmacokinetics in normal and morbidly obese subjects.  Antimicrob Agents Chemother 21:575-580, 1982.

19. Blouin RA, Erwin WG, Foster TS, Scott S:  Pharmacokinetics of theophylline in young and elderly subjects.  Gerontology 28:323-327, 1982.

20. Hamann SR, Oeltgen PR, Shank WA, Blouin RA, Natarajan L:  Evaluation of gentamicin pharmacokinetics during peritoneal dialysis.  Ther Drug Monitor 4:297-300, 1982.

21. Bauer LA, Blouin RA:  Age and phenytoin kinetics in adult epileptics.  Clin Pharmacol Ther 31:301-304, 1982.

22. Bauer LA, Blouin RA:  Gentamicin pharmacokinetics:  Effect of aging in patients with normal renal function.  J Am Geriatr Soc 30:309-311, 1982.

23. Bauer LA, Blouin RA:  Amikacin pharmacokinetics in young men with pneumonia.  Clin Pharm 1:353-355, 1982.

24. Bauer LA, Piecoro JJ, Wilson HD, Blouin RA:  Gentamicin and tobramycin pharmacokinetics in patients with cystic fibrosis.  Clin Pharm 2:262-264, 1983.

25. Bauer LA, Blouin RA:  Influence of age on amikacin pharmacokinetics in patients without renal disease: Comparison with gentamicin and tobramycin.  Eur J Clin Pharmacol 24:639-642, 1983.

26. Benedek IH, Fiske WD, Griffen WO Jr., Bell RM, ,Blouin RA, McNamara PJ:  Serum alpha-1 acid glycoprotein and the binding of drugs in obesity.  Br J Clin Pharmacol 16:751-754, 1983.

27. Bauer LA, Blouin RA:  Phenytoin Michaelis-Menton pharmacokinetics in Caucasian paediatric patients.  Clin Pharmacokinet 8:545-549, 1983.

28. Hamann SR, Blouin RA, McAllister RG:  Clinical pharmacokinetics of verapamil.  Clin Pharmacokinet 9:26-41, 1984.

29. Benedek IH, Blouin RA, McNamara PJ:  Influence of smoking on serum protein composition and the protein binding of drugs.  J Pharm Pharmacol 36:214-216, 1984.

30. Bauer LA, Edwards WA, Randolph FP, Blouin RA:  Cimetidine induced decreases in lidocaine metabolism.  Am Heart J 108:413-415, 1984.

31. Oeltgen PR, Shank WA, Blouin RA, Clark T:  Clinical evaluation of the Abbott TDx(TM) fluorescence polarization immunoassay analyzer.  Ther Drug Monit 6:360-367, 1984.

32. O'Neal W, Whitten KM, Baumann RJ, Blouin RA, Piecoro JJ:  Lack of serious toxicity following carbamazepine overdose.  Clin Pharm 3:545-547, 1984.

33. Brouwer KL, Kostenbauder HB, McNamara PJ, Blouin RA:  Phenobarbital in the genetically obese Zucker rat. I.  Pharmacokinetics after acute and chronic administration.  J Pharmacol Exp Ther 231:649-653, 1984.

34. Brouwer KL, Kostenbauder HB, McNamara PJ, Blouin RB:  Phenobarbital in the genetically obese Zucker rat. II.  In Vivo and In Vitro assessments of microsomal enzyme induction.  J Pharmacol Exp Ther 231:654-659, 1984.

35. Benedek IH, Blouin RA, McNamara PJ:  Serum protein binding and the role of increased alpha 1-acid glycoprotein in moderately obese male subjects.  Br J Clin Pharmacol 18:941-946, 1984.

36. Hamann SR, Blouin RA, Chang SL, Kaltenborn KE, Tan TG, McAllister RG:  Effects of hemodynamic changes on the elimination kinetics of verapamil and nifedipine.  J Pharmacol Exp Ther 231:301-305, 1984.

37. Blouin RA, Brouwer KL, Record KE, Griffen WO Jr., Plezia PM, John W:  Amikacin pharmacokinetics in morbidly obese patients undergoing gastric by-pass surgery.  Clin Pharm 4:70-72, 1985.

38. Hamann SR, Tan TG, Kaltenborn KE, Brouwer KLR, Blouin RA, Chang SL, Vore M, McAllister RG:  Effects of phenobarbital and SKF-525A on In Vitro hepatic metabolism of verapamil and nifedipine.  Pharmacology 30:121-128, 1985.

39. Oeltgen PR, Blouin RA, Spurrier WA, Myers RD:  Hibernation "Trigger" alters renal function in the primate.  Physiol Behav 34:79-81, 1985.

40. McAllister RG, Hamann SR, Blouin RA:  Pharmacokinetics of calcium entry blockers.  Am J Cardiol 55:30B-40B, 1985.

41. Gibson GA, Blouin RA, Bauer LA, Rapp RP, Tibbs PA:  Influence of high dose pentobarbital on theophylline pharmacokinetics: a case report.  Ther Drug Monitor 7:181-184, 1985.

42. Benedek IH, Blouin RA, McNamara PJ:  Altered drug-serum protein binding in the genetically obese Zucker rat.  J Pharm Sci 74:837-840, 1985.

43. Wermeling D, Record K, Bell R, Porter W, Blouin RA:  Hemodialysis clearance of pentobarbital during continuous infusion:  A case report.  Ther Drug Monit 7:485-487, 1985.

44. Michael KA, Mohler JL, Blouin RA, Lucas BA, Rapp RP:  Failure of creatinine clearance to predict gentamicin half-life in a renal transplant patient with diabetes mellitus.  Clin Pharm 4:572-575, 1985.

45. Mohler JL, Barton SD, Blouin RA, Cowen DL, Flanigan RC:  The evaluation of creatinine clearance in spinal cord injured patients.  J Urology 136:366-369, 1986.

46. Fiske WD, Blouin RA, Mitchell B, McNamara PJ:  Renal function in the obese Zucker rat.  Int J Obes 10:175-183, 1986.

47. Wermeling DP, Blouin RA, Porter WH, Rapp RP, Tibbs PA:  Pentobarbital pharmacokinetics in patients with severe head injury.  Drug Intell Clin Pharm 21:459-463, 1987.

48. Huang Chandler MH, Guttendorf RJ, Blouin RA, Wedlund PJ:  Simultaneous quantitation of d- and l-hexobarbital in rat blood by HPLC.  J Chromatogr 419: 426-432, 1987.

49. Blouin RA, Kolpek JH, Mann HJ:  Influence of obesity on drug disposition.  Clin Pharm 6:706-714, 1987.

50. Blouin RA, Dickson P, McNamara PJ, Cibull M, McClain C:  Phenobarbital induction and acetaminophen hepatotoxicity:  resistance in the obese Zucker rodent.  J Pharmacol Exp Ther 243:565-570, 1987.

51. Clifton GD, Blouin RA, Dilea C, Schran HF, Hassell AE, Gonasun LM, Foster TS:  The pharmacokinetics of oral isradipine in normal volunteers.  J Clin Pharmacol 28:36-42, 1988.

52. Chandler MH, Scott SR, Blouin RA:  Age-associated stereoselective alterations in hexobarbital metabolism.  Clin Pharmacol Ther 43:436-441, 1988.

53. McNamara PJ, Blouin RA, Brazzell RK:  The protein binding of phenytoin, propranolol, diazepam and AL01576 (an aldose reductase inhibitor) in human and rat diabetic serum.  Pharm Res 5:261-265, 1988.

54. McNamara PJ, Blouin RA, Brazzell RK:  Serum protein binding of AL01576, a new aldose reductase inhibitor.  Pharm Res 5:319-321, 1988.

55. Chandler MH, Blouin RA:  Theophylline pharmacokinetics in the aged:  A review.  J Geriatric Drug Ther 3:23-40, 1988.

56. Chandler MH, Schran HF, Cutler RE, Smith AJ, Gonasun LM, Blouin RA:  The effects of renal function on the disposition of isradipine.  J Clin Pharmacol 28:1076-1080, 1988.

57. Heintz RC, Ducarre JM, Blouin RA, Guengi A:  Influence of oral dose escalation on the pharmacokinetics of tenoxicam [Tilcotil] in healthy male subjects.  Eur J Rheum Inflam 9-15, 1988.

58. Colangelo P, Chandler M, Blouin R, McNamara P:  Stereoselective binding of propranolol.  Br J Clin Pharmacol 27:519-522, 1989.

59. Blouin RA, Kneer J, Stoeckel K:  Pharmacokinetics of cefetamet (RO15-8074) and oral sefetamet pivoxil (RO15-8075) in young and elderly subjects.  Antimicrob Ag Chemoth 33:291-296, 1989.

60. Foster TS, Kielar RA, Blouin RA, Parr MD, Barton S, Perchak GJ, Johnson JB:  Maintenance of previously controlled intraocular pressure in patients with glaucoma or ocular hypertension:  Comparison of four regimens of methazolamide.  Glaucoma 11:67-71, 1989.

61. Blouin RA, Clifton GD, Adams MA, Foster TS, Flueck J:  Biopharmaceutical comparison of two levothyroxine sodium products.  Clin Pharm 8:588-592, 1989.

62. Kneer J, Tam YK, Blouin RA, Frey FJ, Keller E, Stathakis C, Luginbuehl B, Stoeckel K:  Pharmacokinetics of intravenous cefetamet and oral cefetamet pivoxil in patients with renal insufficiency.  Antimicrob Agents Chemother 33:1952-1957, 1989.

63. Hatton J. Parr MD, Blouin RA:  Estimation of creatinine clearance in patients with Cushing's Syndrome.  Drug Intell Clin Pharm 23:974-976, 1989.

64. Guttendorf RJ, Britto M, Blouin RA, Foster TS, John W, Pittman KA, Wedlund PJ:  Rapid screening for polymorphisms in dextromethorphan and mephenytoin metabolism.  Br J Clin Pharmacol 29:373-380, 1990.

65. McNamara PJ, Blouin RA:  Pharmacokinetic profile of two aromatic retinoids (etretinate and acitretin) in the obese Zucker rats.  J Pharm Sci 79:301-304, 1990.

66. Chandler MH, Clifton GD, Burki NK, Hunt BA, Blouin RA:  Pulmonary function in the elderly: response to theophylline bronchodilation.  J Clin Pharmacol 30:330-335, 1990.

67. Hayton WL, Kneer J, Blouin RA, Stoeckel K:  Pharmacokinetics of intravenous cefetamet and oral cefetamet pivoxil in patients with hepatic cirrhosis.  Antimicrob Agents Chemoth 34:1318-1322, 1990.

68. Schoerlin MP, Blouin RA, Pfefen JP, Guentert TW:  Comparison of the pharmacokinetics of moclobemide in poor and extensive metabolizers of debrisoquine.  Acta Psychiatr Scand Suppl 360:98-100, 1990.

69. Blouin RA, Kneer J, Ambrose RJ, Stoeckel K:  Influence of antacid and ranitidine on the pharmacokinetics of oral cefetamet pivoxil.  Antimicrob Agents Chemoth 34:1744-1748, 1990.

70. Zhang Y, Blouin RA, McNamara PJ, Steinmetz J, Wedlund PJ:  Limitation to the use of the urinary S/R mephenytoin ratio in pharmacogenetic studies.  Br J Clin Pharmacol 31:350-352, 1991.

71. Colangelo P, Rapp R, Blouin R and Kenady D:  Comparative bioavailability and safety of two parenteral vancomycin formulations.  J N Dev Clin Med 8:11-20, 1991.

72. Blouin RA, Cloyd JC, Ludden TM, Kroboth PD:  Central issues relevant to clinical pharmaceutical scientist training programs.  Pharmacotherapy 11:257-263, 1991.

73. Smith DA, Chandler MH, Shedlofsky SI, Wedlund PJ, Blouin RA:  Age-dependent stereoselective increase in the oral clearance of hexobarbitone isomers caused by rifampin.  Br J Clin Pharmacol 32:735-39, 1991.

74. Blouin RA, Hamelin BA, Smith DA, Foster TS, John WJ, Welker HA:  Fleroxacin pharmacokinetics in patients with liver cirrhosis.  Antimicrob Ag Chemoth 36:632-638, 1992.

75. Colangelo PM, Blouin RA, Steinmetz JE, McNamara PJ, Demaria AN, Wedlund PJ:  Age and propranolol stereoselective disposition in humans.  Clin Pharmacol Ther 51:489-494, 1992.

76. Colangelo PM, Blouin RA, Steinmetz JE, McNamara PJ, Demaria AN, Wedlund PJ:  Age and beta-adrenergic receptor sensitivity to S(-)- and R,S(+/-)-propranolol in humans.  Clin Pharmacol Ther 51:549-554, 1992.

77. Hamelin BA, Blouin RA, Wolf KM, Clifton GD, Chandler MH:  In vivo and in vitro beta-2 adrenergic receptor responsiveness in young and elderly asthmatics.  Pharmacotherapy 12:376-382, 1992.

78. Blouin RA, Chaudhary I, Nishihara K, Cox SA:  The effect of liver and renal disease on stereoselective serum binding of flurbiprofen.  Br J Clin Pharmacol 35:62-64, 1993.

79. Blouin RA:  Issues in pharmacotherapy:  Hepatic cytochrome P450 - Application of animal models to therapeutic problems in humans.  The ACCP Report 13:(2),1993.

80.   Israel BC, Blouin RA, McIntyre W, Shedlofsky SI:  Effects of interferon-alpha monotherapy on hepatic drug metabolism in cancer patients.  Br J Clin Pharmacol 36:229-235, 1993.

81. Blouin RA, Bandyopadhyay AM, Chaudhary I, Robertson LW, Gemzik B, Parkinson A:  Cytochrome P450 2B enzyme (CYP2B) induction defect following phenobarbital treatment in the fa/fa rat: Molecular characterization.  Arch Biochem Biophys 303:313-320, 1993.

82. Chaudhary I, Tuntaterdtum S, McNamara PJ, Robertson LW, Blouin RA:  Effect of genetic obesity and phenobarbital treatment on the hepatic conjugation pathways.  J. Pharmacol. Exp. Ther 265:1333-1338, 1993.

83.  Blouin RA, Stoeckel K:  Cefetamet pivoxil clinical pharmacokinetics.  Clin.Pharmacokinet 25:172-188, 1993.

84.  Zannikos PN, Bandyopadhyay AM, Robertson LW, Blouin RA:  Effect of nutritional obesity on the induction of CYP2B enzymes following phenobarbital treatment.  Drug Metab Dispos 21:782-787, 1993

85. Toler SM, Young B, McClain CJ, Shedlofsky SI, Bandyopadhyay AM, Blouin RA:  Head injury and cytochrome P-450 enzymes.  Differential effects on mRNA and protein expression in the Fischer-344 rats.  Drug Metab Dispos 21:1064-1069, 1993.

86. Bandyopadhyay AM, Chaudhary I, Robertson LW, Gemzik B, Parkinson A, Blouin RA:  Expression of a male-specific cytochrome P450 isozyme (CYP2C11) in fa/fa Zucker rats: effect of phenobarbital treatment.  Arch Biochem Biophys 307:386-390, 1993.

87. Tuntaterdtum S, Chaudhary I, Cibull ML, Robertson LA, Blouin RA:  Acetaminophen hepatotoxicity: influence of phenobarbital and ß-naphthoflavone treatment in obese and lean Zucker rats.  Toxicol Appl Pharmacol 123:219-225, 1993.

88. Zannikos PN, Bandyopadhyay AM, Robertson LW, Blouin RA:  Expression of the CYP3A and CYP2C11 enzymes in a nutritionally obese rodent model: response to phenobarbital treatment.  Int J Obes Relat Metab Disord 18:369-374, 1994.

89.  Zannikos PN, Bandyopadhyay AM, Robertson LW, Blouin RA:  Cytochrome P450 2B enzyme induction defect after 2,2’,4,4’,5,5’-hexachlorobiphenyl treatment in the fa/fa Zucker rat.  J Pharmacol Exp Ther 268:1565-1570, 1994.

90.  Blouin RA, McNamara PJ, Chandler MHH, Kostenbauder HB:  Development of a clinical pharmacology program at the University of Kentucky College of Pharmacy.  Am J Pharm Educ 58:289-293, 1994.

91. Shedlofsky SI, Israel BC, McClain CJ, Hill DB, Blouin RA:  Endotoxin administration to humans inhibits hepatic cytochrome P450-mediated drug metabolism.  J Clin Invest 94:2209-2214, 1994.

92.   Chen S, Chou W, Blouin RA, Mao Z, Humphries LL, Meek QC, Neill JR, Martin WL, Hays LR, Wedlund PJ:  The cytochrome P450-2D6 (CYP2D6) enzyme polymorphism: screening costs and influence on clinical outcomes in psychiatry.  Clin Pharmacol Ther 60:522-534, 1996.

93.  Roe AL, Blouin RA, Howard G:  In vivo phenobarbital treatment increases protein binding to a putitive AP-1 site in the CYP2B2 promoter.  Biochem Biophys Res Commun 228:110-114, 1996.

94.  Shedlofsky SI, Israel BC, Tosheva R, Blouin RA:  Endotoxin depresses hepatic cytochrome P450-mediated drug metabolism in women.  Br J Clin Pharmacol 43:627-632, 1997.

95.   Rees WA, Harkins JD, Woods WE, Blouin RA, Lu M, Fenger C, Holland RE, Chambers TM, Tobin T:  Amantadine and equine influenza: Pharmacology, pharmacokinetics, and neurological effects in the horse.  Equine Vet J 29(2):104-110, 1997.

96 Roe AL, Howard G, Hou G, Howard G, Shedlofsky S, Blouin RA:  The effect of high dose endotoxin on CYP3A2 expression in the rat.  Pharm Res 15:1603-1608, 1998.

97. Stoeckel K, Hofheinz W, Laneury JP, Duchene P, Shedlofsky SI, Blouin RA:  Stability of cephalosporin prodrug esters in human intestinal juice:  Implications for oral bioavailability.  Antimicrob Agents Chemother 42:2602-2606, 1998.

98. Roe AL, Howard G, Blouin RA:  Characterization of nuclear protein binding (AP-1, GR, and STAT) in the genetically obese (fa/fa) Zucker rat.  Life Sci 63:1339-1346, 1998.

99. Blouin RA, Warren GW:  Pharmacokinetic considerations in obesity.  J. Pharm. Sci 88:1-7, 1999.

100. Roe AL, Howard G, Blouin RA, Snawder JE:  Characterization of cytochrome P450 and glutatione S-transferase activity and expression in male and female ob/ob mice.  Int. J. Obesity 23:48-53, 1999.

101. Watson AM, Warren G, Howard G, Shedlofsky SI, Blouin RA:  Activities of conjugating and antioxidant enzymes following endotoxin exposure.  J Biochem Mol Toxicol 13:63-69, 1999.

102. Warren GW, Poloyac SM, Gary DS, Mattson MP, Blouin RA:  Hepatic cytochrome P-450 expression in the tumor necrosis factor-alpha rceptor (p55/p75) knockout mice after endotoxin administration.  J Pharmacol Exp Ther 288:945-950, 1999.

103.  Blouin RA, Farrell GC, Ioannides C, Renton K, Watlington CO:  Impact of diseases on detoxification.  J Biochem Mol Toxicol 13:215-218, 1999.

104. Watson AM, Poloyac SM, Howard G, Blouin RA:  The effect of leptin on cytochrome P-450, conjugation, and antioxidant enzymes in the ob/ob mouse.  Drug Metab Dispos 27 (6):695-700, 1999.

105. Lu M, Poloyac SM, McNamara PJ, Blouin RA:  The effect of pregnenolone 16 alpha-carbonitrile on the pharmacokinetics and metabolism of dapsone in rats.  J Pharm & Pharmacol 51:803-810, 1999.

106. Rockich K, Blouin RA:  The effect of the acute phase response on the pharmacokinetics of chlorzoxazone and cytochrome P450 2E1 in vitro activity in rats.  Drug Metab Dispos 27:1074-1077, 1999.

107. Rockich K, Hatton J, Kryscio D, Young B, Blouin RA:  Effect of intravenous infusion of rhIGF-1 and daily subcutaneous rhGH and IGFBP-3 levels in brain injury.  Pharmacotherapy 19:1432-1436, 1999.

108. Poloyac SM, Tosheva RT, Shedlofsky SI, Blouin RA:  The effect of endotoxin administration on the pharmacokinetics of chlorzoxazone in humans.  Clin Pharmacol Ther 66:554-562, 1999

109. Poloyac SM, Perez-Rivera AA, Scheff S, Blouin RA:  Tissue specific alterations in the 6-hydroxylation of chlorzoxazone following traumatic brain injury in the rat.  Drug Metab Dispos 29:296-298, 2001.

110. Oakley GG, Roe AL, Blouin RA, Twaroski TP, Ganguly TC, Vore M, Lehmler H-J, Robertson LW:  2,4,4’-Trichlorobiphenyl increases STAT5 transcriptional activity.  Mol Carcinog 30:199-208, 2001.

111. Warren GW, Van Ess P, Watson AM, Mattson MP, Blouin RA:  Cytochrome P450 and antioxidant activity in interleukin-6 knockout mice after induction of the acute phase response.  J Interferon Cytokine Res 21:821-826, 2001.

112. Roe AL, Poloyac SM, Howard G, Shedlofsky SI, Blouin RA:  The effect of endotoxin on hepatic nuclear factor 1 nuclear protein binding: potential implications on CYP2E1 expression in the rat.  J Pharm Pharmacol 53:1365-1371, 2001.

113. Van Ess PJ, Pedersen WA, Culmsee C, Rowley D, Mattson MP, Blouin RA:  Elevated hepatic and depressed renal cytochrome P450 activity in the Tg2576 transgenic mouse model of Alzheimer’s disease. J Neurochem 80: 571-578, 2002.

114. Van Ess PJ, Mattson MP, Blouin RA:  Enhanced induction of cytochrome P450 enzymes and CAR binding in the TNF (p55-/-/p75-/-) double receptor knockout mice following Phenobarbital treatment.  J Pharmacol Exp Ther 300: 824-830, 2002.

115. Van Ess PJ, Poloyac SM, Mattson MP, Blouin RA:  Blunted induction of hepatic CYP in TNF (p55-/-/p75-/-) double receptor knockout mice following clofibrate treatment.  Pharm Res 19:709-713, 2002.

116. Rockich KR, Tosheva R, Cunningham C, Goeger D, Blouin RA, Shedlofsky S:  The effect of endotoxin administration on three putative CYP3A markers in human subjects.  (Submitted).