Robert Blouin
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Abstracts/Posters/Presentations
1. Blouin RA: "Development of a Clinical Pharmacokinetics Drug Monitoring Program", Medical University of South Carolina, Charleston, SC, October 1978 (presentation).
2. Blouin RA: "Clinical Pharmacokinetics - Concepts in Theophylline Monitoring", Hamot Medical Center, Erie, PA, November 1978 (presentation).
3. Blouin RA: "Obtaining Third Party Reimbursement for Clinical Services: A Panel Discussion", 13th Annual ASHP Midyear Clinical Meeting, San Antonio, TX, December 1978 (presentation).
4. Blouin RA: "Rational Use of Drug Blood Levels", Northwestern Society of Hospital Pharmacists, Erie, PA, November 1978 (presentation).
5. Blouin RA: "Application of Drug Blood Levels in the Clinical Setting", Southeast Kentucky Baptist Hospital Medical Staff Conference, Corbin, KY, January 1979 (presentation).
6. Blouin RA: "Theophylline Pharmacokinetics", Ohio Society of Hospital Pharmacists Mansfield, OH, June 1979 (presentation).
7. Blouin RA: "The Pharmacist and the Asthmatic Patient", Kentucky Society of Hospital Pharmacists, Louisville, KY, May 1979 (presentation).
8. Blouin RA, Foster TS, Smith RB, and Kostenbauder HB: "Multidisciplinary Approach Towards the Teaching of Clinical Pharmacokinetics", AACP Annual Meeting, Denver, CO, July 1979 (poster).
9. Blouin RA: "Aminoglycoside Pharmacokinetics", Morehead Clinic, Morehead, KY, October 1979 (presentation).
10. Dutro MP, Blouin RA, Erwin WG, Bustrack JA, Rowse KL: "Chloramphenicol Clearance and Protein Binding During Hemodialysis", ASHP Midyear Clinical Meeting, Las Vegas, NV, December 1979 (poster).
11. Dionne RE, Gibson GA, Bauer LA, Blouin RA, and Griffen WO: "Evaluation of Methods to Estimate Creatinine Clearance in Morbidly Obese Patients", ASHP Midyear Clinical Meeting, Las Vegas, NV, December 1979 (poster).
12. Blouin RA, Bauer LA, Griffen WO., Jr., Record KE, and Bell RM: "Amikacin Pharmacokinetics in Morbidly Obese Patients", ASHP Midyear Clinical Meeting, Las Vegas, NV, December 1979 (presentation).
13. Blouin RA: "Theophylline Pharmacokinetics", Hunter Foundation for Health Care, Lexington, KY, May 1980 (presentation).
14. Blouin RA: "Bioavailability of Drugs and Clinical Pharmacokinetics", The Institute of Applied Pharmaceutical Science, East Brunswick, NJ, July 1980 (presentation).
15. Oeltgen PR, Hamann SR, Blouin RA: "Comparison of RIA and Emit for the Determination of Serum Gentamicin", American Association for Clinical Chemistry Annual Meeting, Boston, MA, July 1980 (abstract).
16. Bauer LA, Bauer SP, Blouin RA: "Theophylline Clearance in Cigarette Smoking Patients with Renal Failure", ASHP Midyear Clinical Meeting, San Francisco, CA, December 1980 (poster).
17. Blouin RA: "How to Develop and Implement a Clinical Pharmacokinetic Service", ASHP Institute, Atlanta, GA, March 1981 (presentation).
18. Blouin RA: "The Laboratory's Role in Therapeutic Drug Monitoring - Pharmacokinetics in Clinical Practice", University of Kentucky, College of Allied Health Professions, Lexington, KY, May 1981 (presentation).
19. Blouin RA: "Acetaminophen Overdose" Medicine Conference, St. Joseph's Hospital, Lexington, KY, October 1981 (presentation).
20. Blouin RA: "Application of Clinical Pharmacokinetics of Theophylline", Third Annual Open Forum, Toledo, OH, November 1981 (presentation).
21. Blouin RA: "Development of a Theophylline Pharmacokinetic Service", Fourteenth Annual Expanding Hospital Pharmacy Services Seminar, Toledo, OH, November 1981 (presentation).
22. Rowse KL, Blouin RA, Record KE, Griffen WO, John W: "Effect of Surgery on the Pharmacokinetics of Amikacin in Morbidly Obese Patients", ASHP Midyear Clinical Meeting, New Orleans, LA, December 1981 (poster).
23. Blouin RA: "How to Develop and Implement a Clinical Pharmacokinetics Service", ASHP Institute, Cleveland, OH, August 1982 (presentation).
24. Blouin RA: "Management of the Aged: Pharmacokinetic Considerations" ASHP Midyear Clinical Meeting, Los Angeles, CA, December 1982 (presentation).
25. Bauer LA, Blouin RA: "Phenytoin Michaelis - Menten Kinetics in Caucasian Pediatric Patients", American Society for Clinical Pharmacology and Therapeutics, San Diego, CA, March 1983 (poster).
26. Fiske WD, Blouin RA, McNamara, PJ: "P-aminohippurate and Glucose Interaction", APhA Annual Meeting, New Orleans, LA, April 1983 (poster).
27. Benedek IH, Fiske WD, Griffen WO Jr., Blouin RA, McNamara PJ: "Serum Protein Binding of Drugs and Obesity", APhA Annual Meeting, New Orleans, LA, April 1983 (poster).
28. Rowse KL, Kostenbauder HB, McNamara PJ, Blouin RA: "Pharmacokinetics of Phenobarbital in Obese Zucker, Lean Zucker and Sprague-Dawley Rats", APhA Annual Meeting, New Orleans, LA, April 1983 (poster).
29. Blouin RA: "Introduction to Pharmacokinetics", Bristol Laboratories, Syracuse, NY, July 1983 (presentation).
30. Mays-Whitten K, O'Neal W, Piecoro J, Baumann R, Blouin RA: "Carbamazepine Overdosage: A Case Report", ASHP Midyear Clinical Meeting, Atlanta, GA, December 1983 (poster).
31. Blouin RA: "Aminoglycoside Antibiotics", Seventeenth Annual Southwestern Clinical Pharmacy Seminar, Tucson, AZ, February 1984 (presentation).
32. Blouin RA: "Consulting Services and New Technologies", Seventeenth Annual Southwestern Clinical Pharmacy Seminar, Tucson, AZ, February 1984 (presentation).
33. Hamann SR, Blouin RA, Kaltenborn KE, McAllister RG: "Plasma Level - Dependent Clearance of Verapamil During Intravenous Infusion", American Society for Clinical Pharmacology and Therapeutics, Atlanta, GA, April 1984 (abstract).
34. Rowse Brouwer KL, Kostenbauder HB, McNamara PJ, Blouin RA: "Hepatic Drug Metabolism in a Genetically Obese Rodent Model: Altered Response to Phenobarbital (Pb) Treatment", FASEB, St. Louis, MO, April 1984 (abstract).
35. Benedek IH, Blouin RA, McNamara PJ: "Altered Drug Protein Binding in the Serum of a Genetically Obese Zucker Rat", APhA Meeting, Philadelphia, PA, November 1984 (poster).
36. Barton SD, Mohler J, Blouin RA, Rapp RP: "Creatinine Production in Spinal Cord Injured Patients", OCCP & CP, Cincinnati, OH, November 1984 (poster).
37. Blouin RA: "Pharmacokinetic Considerations of the Post-Operative and Burned Patient", California Society of Hospital Pharmacists, San Francisco, CA, November 1984 (presentation).
38. Blouin RA: "Pharmacokinetics Considerations of the Post-Operative and Burned Patient", California Society of Hospital Pharmacists, Los Angeles, CA, November 1984 (presentation).
39. Michael KA, Mohler JL, Blouin RA, Lucas BA, Rapp RP: "Failure of Creatinine Clearance to Predict Gentamicin Half-Life in a Renal Transplant Patient: A Descriptive Report", ASHP Midyear Clinical Meeting, Dallas, TX, December 1984 (poster).
40. Blouin RA, Fiske WD, McNamara PJ: "Renal Function in the Genetically Obese Zucker Rat", FASEB, Anaheim, CA, April 1985 (accepted).
41. Blouin RA: "Renal Function in Obesity - Clinical Implications", Research and Seminar Series, Augusta, GA, February 1985 (presentation).
42. Blouin RA: "Biopharmaceutic and Pharmacokinetic Considerations of Drug Product Selection", Virginia Society of Hospital Pharmacists, Richmond, VA, November 1985 (presentation).
43. Kolpek J, Blouin RA, Parr M: "Alteration in Creatinine Production Rates in Cushingoid Patients", ASHP Midyear Clinical Meeting, New Orleans, LA, December 1985 (poster).
44. Foster TS, Blouin RA, Hobbs S, McAllister RG: "Dose Proportionality of Nifedipine: A Single Escalating Intravenous Dose Study in Man", ACCP, Chicago, IL, July 1986 (poster).
45. Blouin RA, McNamara PJ, Dickson P, McClain C, Cibull M: "Resistance to Acetaminophen Hepatotoxicity in the Obese Zucker Rodent", AAPS, Washington, DC, November 1986 (poster).
46. Chandler MHH, Guttendorf RJ, Wedlund PJ, Blouin RA: "Simultaneous Quantitation of d- and l-Hexobarbital in Rat Blood by High Performance Liquid Chromatography", AAPS, Washington, DC, November 1986 (poster).
47. McNamara PJ, Blouin RA, Brazzell RK: "Drug Protein Binding in Diabetic and Non-Diabetic Serum", AAPS, Washington, DC, November 1986 (poster).
48. McNamara PJ, Blouin RA, Brazzell RK: "Serum Protein Binding of ALO1576, A New Aldose Reductase Inhibitor", AAPS, Washington, DC, November 1986 (poster).
49. Blouin RA: Overview of Drug Pharmacology in the Elderly, "Life After Fifty Gerontology Fair", Bowling Green, KY, September 1986 (presentation).
50. Blouin RA: "Clinical Pharmacokinetic Monitoring: Past, Present and Future", KSHP, Louisville, KY, May 1987 (presentation).
51. Guttendorf RJ, Chandler MHH, Blouin RA, Wedlund PJ: "Effect of Age on Hexobarbital Stereoselective Disposition in the Rat", AAPS, Boston, MA, June 1987 (poster).
52. Guttendorf RJ, Blouin RA, Foster TS, Wedlund PJ: "Dextromethorphan Mephenytoin: Influence of Co-Administration on Patient Phenotyping", AAPS, Boston, MA, June 1987 (poster).
53. Chandler MHH, Schran HF, Proskin HM, Gonasun LM, Smith AJ, Foster TS, Hobbs SN, Blouin RA: "Effects of Renal Function on the Disposition of Isradipine" ACCP, Austin, TX, July 1987 (poster).
54. Blouin RA: "Clinical Complications in Drug Dosing", Kentucky Academy of Family Physicians, Owensboro, KY, July, 1987 (presentation).
55. Chandler MHH, Scott SC, Blouin RA: "Age-Dependent Stereoselective Alterations in Hexobarbital Metabolism", American Society of Clinical Pharmacology and Therapeutics, San Diego, CA, March 1988 (poster).
56. Jones P, Chaudhary I, Robertson L, Blouin RA: "Molecular Basis of Inducibility of cyt P-450 in Obese Rodent Model", Society of Toxicology, Dallas, TX, February 1988 (poster).
57. Chaudhary I, McNamara PJ, Blouin RA: "Acetaminophen Hepatotoxicity in Obese Zucker Rats: Mechanism of Resistance", Society of Toxicology, Dallas, TX, February 1988 (poster).
58. Blouin RA, Stoeckel K: "Pharmacokinetic Comparison of Fluoroquinolones", International Congress for Infectious Disease, Rio de Janeiro, April 1988.
59. Kneer J, Blouin R, Keller E, Stathakis C, Stoeckel K: "Pharmacokinetics of Cefetamet in Patients with Renal Insufficiency", 6th Mediterranean Congress of Chemotherapy, Taormena-Giardini Naxos, Italy, May 1988 (poster).
60. Chaudhary I, McNamara PJ, Blouin RA: "Effect of Phenobarbital Induction on Acetaminophen Kinetics in Obese Zucker Rat", AAPS, Orlando, FL, November 1988 (poster).
61. Blouin RA, Foster TS, Wedlund PJ, John W, Kolpek J, Robbins D, Cox SR: "Drug Metabolism of Flurbiprofen Enantiomers in Liver Disease", AAPS, Orlando, FL, November 1988 (poster).
62. Blouin RA: "Age Related Stereoselective Alterations in Hexobarbital Metabolism", Idaho State University, Pocatello, ID, November 1988 (seminar).
63. Blouin RA: "Clinical Scientists: Are They Needed?" Idaho State University, Pocatello, ID, November 1988 (seminar).
64. Chandler MHH, Clifton GD, Blouin RA, Hunt BA, Burki NK: "Pulmonary Function in Elderly: Response to Theophylline Bronchodilation", ASCPT, Nashville, TN, March 1989 (poster).
65. Chaudhary I, Robertson L, Blouin RA: "Enzyme Induction Defect to Phenobarbital in the fa/fa Zucker Rat: Relation Between Cytochrome P-450 and UDPGT", SOT, Atlanta GA, March 1989 (poster).
66. Chen LC, Chaudhary I, Blouin RA, Chow CK: "Effect of Acetaminophen on Hepatic Antioxidant Status of Zucker Rats", FASEB, New Orleans, LA, March 1989 (poster).
67. Smith DA, Chandler MHH, Shedlofsky S, Wedlund PJ, Blouin RA: "Stereoselective Induction of Hexobarbital with Rifampin", ASCPT, Nashville, TN, March 1989 (poster).
68. Blouin RA: "Relevance of Animal Models to Human Pharmacokinetics: An Example", ASCPT Symposium on Pharmacokinetics and Pharmacodynamics, Nashville, TN, March 1989 (Symposia presentation).
69. Blouin RA, Smith DA, Chandler MHH, Shedlofsky SI, Wedlund PJ: "The Effects of Rifampin Treatment on the Stereoselective Metabolism of Hexobarbital in Young and Elderly Subjects", IV World Conference in Clinical Pharmacology & Therapeutics, Heidleberg, Germany, July, 1989 (poster).
70. Blouin RA: "Stereoisomerism - Practical Considerations", ACCP Symposium on Drug Stereochemistry: What the Science Means to the Clinician, Kansas City, MO, August 1989.
71. Blouin RA: "Clinical Scientist Program", ACCP, Kansas City, MO, August 1989 (roundtable discussion).
72. Smith DA, Chandler MHH, Shedlofsky SI, Wedlund PJ, Blouin RA: "The Effects of Rifampin Induction on the Stereoselective Metabolism of Hexobarbital in the Young and Elderly", ACCP, Kansas City, MO, August 1989 (presentation).
73. Foster TS, Blouin RA: "The Effect of Antacid Timing on Lomefloxacin Bioavailability", Houston, TX, September 1989 (poster).
74. Blouin RA: "Influence of Obesity on Xenobiotic Metabolism", Ohio Valley Society of Toxicology, Cincinnati, OH, May 1989 (Symposia presentation).
75. Kneer J, Tam YK, Blouin RA, Stoeckel K: "The Influence of Food and Fluid Intake on the Absorption of Cefetamet Pivoxil", International Congress of Chemotherapy, Jerusalem, Israel, June 1989 (poster).
76. Wedlund PJ, Zhang Y, Britto M, Blouin RA, McNamara PJ, Steinmetz J, DeMaria AN: "Polymorphic Oxidative Metabolism of S-Mephenytoin", ASCPT, San Fransisco, CA, March 1990 (poster).
77. Colangelo P, Blouin RA, McNamara PJ, Wedlund PJ, Steinmetz J, Demaria AN: "Age and Its Effect on Propranolol Stereoselective Oral Clearance", ASCPT, San Fransisco, CA, March 1990 (poster).
78. Blouin RA: "Stereoselective Drug Metabolism", Therapeutics and Pharmacokinetics in the 1990's, Breckenridge, CO, March 1990 (Symposia presentation).
79. Kneer J, Blouin RA, Stoeckel K: "The Influence of Antacid and Ranitidine Administration on the Pharmacokinetics of Oral Cefetamet Pivoxil", the 7th Mediterranean Congress of Chemotherapy, Barcelona, Spain, May 1990 (poster).
80. Chaudhary I, Parkinson A, Robertson LW, Blouin RA: "Phenobarbital Induction Defect in the Obese Zucker Rat I", AAPS, Las Vegas, NV, November 1990 (poster).
81. Chaudhary I, Parkinson A, Robertson LW, Blouin RA: "Phenobarbital Induction Defect in the Obese Zucker Rat II", AAPS, Las Vegas, NV, November 1990 (poster).
82. Chaudhary I, Nishihara, K, Robertson LW, Blouin RA: "Phenobarbital Induction Defect in the Obese Zucker Rat III", AAPS, Las Vegas, NV, November 1990 (poster).
83. Chaudhary I, Nishihara K, Robertson LW, Blouin RA: "PCB Induction Defect in the Obese Zucker Rat", AAPS, Las Vegas, NV, November 1990 (poster).
84. Hallak HO, Wedlund PJ, Foster TS, Blouin RA, John W, Patel IH: "Midazolam Disposition and Response in Efficient and Poor Metabolizers of Dextromethorphan", ASCPT, San Antonio, TX, March 1991 (poster).
85. Blouin RA: "Phenobarbital in the Genetically Obese Zucker Rat: Differential Induction of Gene Expression", Wayne State University, Detroit, MI, October 1990 (presentation).
86. Blouin RA, Bandyopadhyay AM, Chaudhary I: "Effect of Phenobarbital Treatment on Cytochrome P-450IIC11 mRNA in Obese Zucker Rats", FASEB, Atlanta, GA, April 1991 (poster).
87. Bandyopadhyay AM, Chaudhary I, Blouin RA: "Molecular Mechanism of Phenobarbital Induction Defect of Cytochrome P-450IIB1/IIB2 in Obese Zucker Rats", FASEB, Atlanta, GA, April 1991 (poster).
88. Chaudhary I, Tuntaterdtum S, Cibull ML, Blouin RA: "Effect of P-450 Inducers on Acetaminophen Hepatotoxicity in Obese Zucker Rats", FASEB, Atlanta, GA, April 1991 (poster).
89. Chandler MHH, Hamelin BA, Clifton GD, Blouin RA, Wolf KM: "Terbutaline Pharmacodynamics in Young and Elderly Asthmatics", ACCP, Minneapolis, MN, August 1991 (poster).
90. Chandler MHH, Hamelin BA, Blouin RA, Clifton GD, Wolf KM: "Responsiveness of Pure T-Lymphocytes to a Beta-2 Agonist in Young and Elderly Asthmatics", ACCP, Minneapolis, MN, August 1991 (poster).
91. Blouin RA: "Central Issues Relevant to Clinical Pharmaceutical Scientist Training Programs", ACCP, Minneapolis, MN, August 1991 (presentation).
92. Nishihara K, Chaudhary K, Cox S, Blouin RA: "Stereoselective Protein Binding of Flurbiprofen in Liver and Renal Disease", AAPS, Washington, DC, November 1991 (poster).
93. Colangelo PM, Blouin RA, Steinmetz JE, McNamara PJ, Wedlund PJ: "Effect of Age on Propranolol Stereoselective Disposition in Man", AAPS, Washington, DC, November 1991 (poster).
94. Colangelo PM, Blouin RA, Steinmetz JE, McNamara PJ, Wedlund PJ: "Effect of Age on Propranolol Enantiomer Pharmacodynamics in Man", AAPS, Washington, DC, November 1991 (poster).
95. Blouin RA: "Management of Drugs in the Elderly", University of Cincinnati Medical Center Geriatrics/Gerontology Speaking Series, Cincinnati, OH, October 1991 (presentation).
96. Blouin RA: "Stereoselective Drug Metabolism in the Elderly: Pharmacodynamic Considerations", University of Cincinnati, College of Pharmacy, Cincinnati, OH, October 1991 (presentation).
97. Blouin RA: "Obtaining Peer Reviewed Funding: Critical Issues for Young Investigators”, ACCP Winter Meeting, Phoenix, AZ, February 1992 (presentation).
98. Blouin RA: "Factors Influencing the Regulation and Expression of Hepatic Cytochrome P450 2B Enzymes", 1992 AAPS Southeastern Regional Meeting, Wilmington, NC, April 1992 (Symposia presentation).
99. Bandyopadhyay A, Blouin RA: "Phenobarbital Induction Defect of Cytochrome P450 2B1/2B2 in Obese Zucker Rat in Hepatocyte Culture", FASEB, Anaheim, CA, April 1992 (poster).
100. Toler SM, Young BA, Bandyopadhyay A, Blouin RA: "The Effect of Head Trauma on Hepatic Cytochrome P-450 in the Fisher-344 Rat", AAPS 1992 Southeast Regional Meeting, Wilmington, NC, April 1992 (poster).
101. Zannikos PN, Bandyopadhyay A, Blouin RA: "Effect of Chronic High Fat Diet on the Expression/Regulation of the Hepatic Cytochrome P-450 System", AAPS 1992 Southeast Regional Meeting, Wilmington, NC, April 1992 (poster).
102. Israel BC, Shedlofsky SI, Swim A, Blouin RA: "Decreased Theophylline and Antipyrine Clearance in Cancer Patients Treated with Interferon-A (IFN)", ACCP, Toronto, Canada, August 1992 (poster).
103. Toler SM, Young BA, Bandyopadhyay A, Blouin RA: "The Effect of Head Trauma on Hepatic CYP3A and CYP2C11 in the Fisher-344 Rat", 1992 Midwest Cytochrome P450 Symposium, Lafayette, IN, September 1992 (poster).
104. Zannikos PN, Bandyopadhyay A, Blouin RA: "Effect of Chronic High Fat Diet on the Expression/Regulation of the Hepatic CYP2B1/2B2", 1992 Midwest Cytochrome P450 Symposium, Lafayette, IN, September 1992 (poster).
105. Blouin RA, Bandyopadhyay A, Chaudhary I, Robertson LW, Gemzick B, Parkinson A: "CYP2B Enzyme Induction Defect: Molecular Characterization”, 1992 Midwest Cytochrome P450 Symposium, Lafayette, IN, September 1992 (poster).
106. Israel BC, Shedlofsky SI, Swim A, Blouin RA: Effects of Endotoxin Induced Sepsis on Cytochrome P-450 Drug Metabolism”, ACCP Annual Meeting, Reno, NV, August 1993 (presentation).
107. Blouin RA: "Stereoselective Drug Metabolism”, Fourth International Symposium on Chiral Discrimination, Montreal, Quebec, September 1993 (Symposia presentation).
108. Zannikos PN, Bandyopadhyay AM, Robertson LW, Blouin RA: "CYP2B Enzyme Induction following Treatment with 2,2’,4,4’,5,5’- Hexachlorobiphenyl in the obese Zucker rat”, AAPS, Orlando, FL, November 1993 (poster).
109. Nishihara KK, McNamara PJ, Blouin RA: "Expression of CYP2B Enzymes: Comparison of Concentration-Response Relationships in Young & Adult Rats”, AAPS, Orlando, FL, November 1993 (poster).
110. Ma Li, Cohen DA, Blouin RA: "The Effect of Murine Acquired Immunodeficiency Syndrome (MAIDS) on Hepatic Microsomal Steroid Hydroxylase Activities”, AAPS, Orlando, FL, November 1993 (poster).
111. Shedlofsky SI, Israel BC, Swim AT, Denison MG, Hill DB, McClain CJ, Blouin RA: "Decreased Hepatic P450-Mediated Drug Clearances in Humans Given Endotoxin (LPS) as a Model of Gram-Negative Sepsis”, AASLD, Chicago, IL, November 1993 (poster).
112. Blouin RA: "Research in Clinical Sciences”, 11th Annual Merrillville Symposium on Pharmaceutical Sciences Graduates Programs, Merrillville, IN, October 1993 (Symposia presentation).
113. Israel BC, Shedlofsky SI, Blouin RA: "Evaluation of an Animal Model of Sepsis: Effect on Hepatic P450 Expression”, ACCP Annual Meeting, St. Louis, MO, August 1994 (poster).
114. Blouin RA: "Mechanism(s) of Phenobarbital Induction: Applications of a Mutant Rodent Model”, University of Alberta, Edmondton, Alberta, April 1994 (presentation).
115. Roe AL, Howard G, Blouin RA: "The Effect of Acute and Chronic In Vivo Phenobarbital Treatment on DNA Binding Proteins”, 10th International Symposium on Microsomes & Drug Oxidation, Toronto, Ontario, July 1994 (poster).
116. Young B, McClain CJ, Kindy M, Dempsey R, Blouin R, Gillespie M, Scheff S: "Pneumatic Impacter Model of Head Injury Simulates Metabolic Aspects of Head Injury”, Congress of Neurosurgical Surgeons, Chicago, IL, October 1994.
117. Roe AL, Howard G, Blouin RA: "Acute and Chronic In Vivo Phenobarbital Treatment Effects on GRE and AP-1 DNA Binding Proteins”, SOT 1995 Annual Meeting, Baltimore, MD, March 1995 (poster).
118. Boni J, Chaudhary I, Batastini G, Tonelli A, Woolcock I, DiStefano F, Vella A, Blouin R, Parkinson A, Eldridge S, Davis H: "A Toxicokinetic and Mechanistic Toxicity Study of CL275,838 (A Novel Memory Enhancing Agent) after Subchronic Dosing in Rats”, AAPS, Miami, Fl, November 1995 (poster).
119. Rees WA, Chambers T, Fenger C, Harkins JD, Blouin RA, Holland R, Tobin T: "The Pharmacokinetics and Bioavailability of Amantidine in the Horse: A Preliminary Report”, Am Assoc Equine Prac. 1995.
120. Blouin RA and Wedlund PJ: "Pharmacokinetics for the Pharmaceutical Scientist: A Short Course”, F. Hoffmann LaRoche, Nutly, NJ, July 1995 (presentation).
121. Blouin RA: "Joint Pharm.D./Ph.D. Programs”, AACP Annual Meeting, Philadelphia, PA, July 1995 (presentation).
122. Israel BC, Shedlofsky SI, Tosheva R, Blouin RA: "Endotoxin Differentially Inhibits Hepatic Cytochrome P450 Drug Metabolism in Female Volunteers”, ACCP Annual Meeting, Washington, DC, August 1995 (presentation).
123. Blouin RA: "Obese Zucker Rodent Model: Responsiveness to Phenobarbital Induction”, 1995 Midwest Cytochromes P450 Symposium, Purdue University, West Lafayette, IN, September 1995 (presentation).
124. Roe AL, Howard G, Shedlofsky SI, Blouin RA: "Cytokine Regulation of CYP3A2 Expression in Rats Treated with LPS”, SOT 1996 Annual Meeting, Anaheim, CA, March 1996 (poster).
125. Lu M, Blouin RA: "Evaluation of Formation Clearance of Dapsone Hydroxylamine as a Marker of CYP3A Activity: An In Vivo and In Vitro Correlation”, AAPS 1996 Annual Meeting, Seattle, WA, October 1996 (presentation).
126. Blouin RA: "Obese Rodent Models: Alterations in Gene Expression of Drug Metabolizing Enzymes”, 1996 Annual Mini-Symposium in Nutritional Sciences, Lexington, KY, April 1996 (presentation).
127. Roe AL, Howard G, Shedlofsky S, Blouin RA: "The Effect of High Dose Endotoxin on Nuclear Protein Binding: Implications on CYP3A2 Regulation”, 1996 Midwest Cytochromes P450 Symposium, Purdue University, West Lafayette, IN, September 1996 (poster).
128. Warren G, Roe AL, Hou J, Shedlofsky S, Blouin RA: "The Effect of High Dose Endotoxin on Hepatic CYP3A2 Regulation”, 1996 Midwest Cytochromes P450 Symposium, Purdue University, West Lafayette, IN, September 1996 (poster).
129. Lu M, Blouin RA: "The Effect of Pregnenolone 16a-Carbonitrile on the Pharmacokinetics and Metabolism of Dapsone”, 1996 Midwest Cytochromes P450 Symposium, Purdue University, West Lafayette, IN, September 1996 (poster).
130. Blouin RA: "The Effect of Head Trauma/Acute Phase Response on Brain and Liver Cytochrome P450 Enzymes”, The Second Annual Kentucky Spinal Cord and Brain Injury Trust Symposium 1996, Lexington, KY, June 1996 (presentation).
131. Lu M, Poloyac SM, Blouin RA: "Evaluation of Oxidation of Dapsone as a Marker of CYP3A Activity: An In Vivo and In Vitro Correlation”, SOT 1997 Annual Meeting, Cincinnati, OH March 1997 (poster).
132. Warren G, Roe AL, Hou J, Shedlofsky S, Blouin RA: "The Effect of High Dose Endotoxin on CYP3A Expression”, SOT 1997 Annual Meeting, Cincinnati, OH March 1997 (poster).
133. Roe AL, Howard G, Shedlofsky S, Blouin RA: "The Effect of High Dose Endotoxin on Nuclear Protein Binding: Implications on CYP3A2 Regulation”, SOT 1997 Annual Meeting, Cincinnati, OH, March 1997 (poster).
134. Blouin RA: "Special Pharmacokinetic Considerations in the Obese Patient”, APhA Annual Meeting, Los Angeles, CA, March 1997 (Symposia presentation).
135. Watson A, Howard G, Shedlofsky S, Blouin RA: "Changes in Conjugation and Antioxidant Enzymes following Endotoxin Exposure”, IUBMB, San Francisco, CA, August 1997 (poster).
136. Roe A, Howard G, Blouin RA: "Constitutive AP-1 Binding Activity in the Genetically Obese (fa/fa) Zucker Rat”, IUBMB, San Francisco, CA, August 1997 (poster).
137. Roe A, Poloyac S, Howard G, Shedlofsky S, Blouin RA: "The Effect of High Dose Endotoxin on Hepatic CYP2E1 Regulation and Expression”, IUBMB, San Francisco, CA, August 1997 (poster).
138. Rockich K, Hatton J, Kryscio R, Young B, Blouin RA: "The effect of Continuous Intravenous Infusion of rhIGF-1 and Daily Subcutaneous Administration of rhGH on IGF-1 and IGFBP-3 Plasma Concentrations in Traumatic Brain Injured Patients”, AAPS, Boston, MA, November 1997 (poster).
139. Oakley GG, Roe AL, Blouin RA, Ganguly T, Vore M, Robertson W: "Activation of AP-1 and STAT Transcription Factors by Non-Coplanar Polychlorinated Biphenyls”, SOT, Seattle, WA, March 1998 (poster).
140. Blouin RA: "Expression and Regulation of Xenobiotic-Metabolizing Enzymes in Obesity”, 12th International Symposium on Microsomes and Drug Oxidations, Montpellier, France, July 1998 (Symposia presentation).
141. Blouin RA: "The Effect of Head Trauma/Acute Phase Response on Brain and Liver Cytochrome P450 Enzymes”, 4th Annual Kentucky Spinal Cord and Head Injury Research Symposium, Lexington, KY, July 1998 (presentation).
142. Rockich K, Blouin RA: "The Effect of the Acute Phase Response on Chlorzoxazone Pharmacokinetics and CYP2E1 Activity in the Rat”, ACCP 1998 Annual Meeting, Cincinnati, OH, November 1998 (poster).
143. Blouin RA: "Relating In-Vitro Data to In-Vivo Drug Interactions”, ACCP 1998 Annual Meeting, Cincinnati, OH, November 1998 (Symposia presentation).
144. Blouin RA: "Translational Research with Drug Interactions”, ACCP 1998 Annual Meeting, Cincinnati, OH, November 1998 (Symposia presentation).
145. Warren G, Mattson M, Blouin RA: "Hepatic Cytochrome P450 Expression in IL-6 Knockout Mice following Endotoxin Administration”, SOT 1999 Annual Meeting, New Orleans, LA, March 1999 (poster).
146. Roe AL, Warren G, Mattson M, Blouin RA: "AP-1 Binding Activity Is Altered in LPS-Treated TNF a (p55/p75) Double Receptor Knockout Mice”, SOT 1999 Annual Meeting, New Orleans, LA, March 1999 (poster).
147. Gardner BM, Poloyac SM, Shedlofsky SI, Blouin RA: “Serum Protein Binding of Chlorzoxazone in Human: The Effect of Endotoxin Administration”, ASHP 1998 Annual Meeting, Las Vegas, NV, December 1998 (poster).
148. Poloyac SM, Tosheva T, RT, Shedlofsky SI, Blouin RA: “Variable Changes in CYP2E1 Activity after Endotoxin Administration in Humans”, SOT 1999 Annual Meeting, New Orleans, LA, March 1999 (poster).
149. Blouin RA: “Post-Graduate Education”, University of Minnesota Seminar Series, Minneapolis, MN, March 1999 (Presentation).
150. Blouin RA: “Prediction Drug-Drug Interactions from In-Vitro Data”, University of Minnesota College of Pharmacy Seminar Series, Minneapolis, MN, March 1999 (Presentation).
151. Van Ess PJ, Pedersen WA, Culmsee C, Mattson MP, Blouin RA: “Alterations in Cytochrome P450 Enzyme Activity in Transgenic Mice Expressing Familial Alzheimer’s Disease-Linked Mutant Beta Amyloid Precursor Protein”, AAPS 1999 Annual Meeting, New Orleans, LA, November 1999 (poster).
152. Poloyac SM, Blouin RA: “Tissues Specific Alterations in CYP2E1 Expression following Traumatic Brain Injury in the Rat”, AAPS 1999 Annual Meeting, New Orleans, LA, November 1999 (poster).
153. Rockich KT, Tosheva T, RT, Shedlofsky SI, Blouin RA: “The Effect of Endotoxin Administration on CYP3A4 Activity in Humans”, AAPS 1999 Annual Meeting, New Orleans, LA, November 1999 (poster).
154. Blouin RA, DiPiro JT, Evans WE, Fletcher CV, Johnson JA, Relling MV: “Establishing the Link: Developing Proposals that Fill a Gap in Knowledge - Mock Study Section: Critique of Contemplated Methods”, 1999 ACCP Annual Meeting, Kansas City, MO, October 1999 (Symposia presentation).
155. Blouin RA: “Understanding Changes in Hepatic Drug Metabolism through Pharmacokinetic Data Analysis of Model Probe Drugs”, 1999 Conference on Nonlinear Statistical Models: Implementation and Application, Lexington, KY, November 1999 (Symposia presentation).
156. Shedlofsky SI, Tosheva RT, Rockich KT, Cunningham CR, Goeger DE, Blouin RA: “Superiority of Midazolam as a Probe for Assessing CYP3A4 Activity in Human Endotoxin Model”, SOT 2000 Annual Meeting, Nashville, TN, March 2000 (poster).
157. Blouin RA: “Expression and Regulation of Drug Metabolizing Enzymes in Obesity”, ASBMB/ASPET Annual Meeting, Boston, MA, June 2000 (Symposia presentation).
158. Lubawy WC, Yokel RA, Blouin RA, Blumenschein K: “Advanced Degree Programs Integrated with the Doctor of Pharmacy Curriculum as a Foundation for the Future”, AACP Annual Meeting, San Diego, CA, July 2000 (poster).
159. Van Ess PJ, Warren GW, Mattson MP, Blouin RA: “Effect of Clofibrate Administration on Cytochrome P450 Activity in TNF p55/p75 Double Receptor Knockout Mice”, AAPS Annual Meeting, Indianapolis, IN, November 2000 (poster).
160. Van Ess PJ, Warren GW, Mattson MP, Blouin RA: “Enhanced Phenobarbital Induction of Hepatic CYP2B Parallels CAR Activation in Tumor Necrosis Receptor Double Knockout Mice”, AAPS Annual Meeting, Denver, CO, November 2001 (poster).
161. Blouin RA (panel member): “Promoting German, Austrian, and Swiss Investment in Kentucky”, Kentucky German Business Council 2nd Annual Conference, Lexington, KY October 2001.
162. Van Ess PJ, Warren GW, Mattson MP, Blouin RA: “Effect of Phenobarbital on Cytochrome P450 Induction in Tumor Necrosis Factor and Interleukin-6 Defficient Mice”, 33rd Annual Pharmaceutical Graduate Student Research Meeting, Madison, WI, July 2001 (Dr. Van Ess received 2nd place poster presentation award for this work).
163. Tosheva RT, Van Ess P, Cunningham CR, Blouin RA, Shedlofsky SI: “Increased CYP2E1 Activity and Enhanced Systemic Oxidative Stress after Endotoxin in Humans”, SOT Annual Meeting, Nashville, TN, March 2002.
164. Van Ess P, Charriez C, Tosheva RT, Shedlofsky SI, Blouin RA: “Correlation between NFkB and Changes in Chlorzoxazone Disposition following an Acute Phase Response”, 2002 ACCP Spring Practice and Research Forum, Savannah, GA, April 2002 (poster).
165. Blouin RA: “The Impact of Obesity on Drug Pharmacokinetics and Pharmacodynamics”, 2002 ACCP Spring Practice and Research Forum, Savannah, GA, April 2002 (presentation).
166. Blouin RA: “The Effect of the Acute Phase Response on CYP2E1 Expression and Regulation”, Department of Medicinal Chemistry Seminar Series, The Ohio State University, Columbus, OH, April 2002 (presentation).
167. Blouin RA: “Effect of Obesity on Drug Metabolism”, University of Kentucky Center for Nutritional Sciences Seminar Series, Lexington, KY April 2002 (presentation).