Primary Faculty

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ken_bastow@unc.edu Associate Professor
Research Interest
Design and development of topoisomerase inhibitors/ antiviral chemotherapy
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jarstfer@email.unc.edu Assistant Professor
Research Interest
Synthetic chemistry, molecular biology, and combinatorial chemistry techniques are used to investigate the ribonucleoprotein telomerase, which plays a pivotal role in tumorgenesis.
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hal_kohn@unc.edu Kenan Professor (Joint appointment with Chemistry Department)
Research Interest
Examination of the biological mechanism of mitomycin C and bicyclomycin at the molecular level; design and synthesis of new chemotherapeutic agents for the treatment of epilepsy, cancer, and bacterial infections.
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drewlee@unc.edu Associate Professor (Joint appointment in Department of Biochemistry and Biophysics)
Research Interest
Using NMR spectroscopy to study the relationship between protein structure and dynamics and how these respond to perturbations such as binding (natural ligands or drugs) and mutation (evolution).
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khlee@unc.edu Kenan Professor
Research Interest
Medicinal chemistry, bioactive natural products, new drug discovery and development, and Chinese medicine.
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jian_liu@unc.edu Associate Professor
Research Interest
Identification of polysaccharide-based receptor; structure and specificity of a heparan sulfate-based herpes simplex virus 1 receptor; drug targeting; gene therapy.
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rliu@email.unc.edu Assistant Professor (Joint appointment with Lineberger Comprehensive Cancer Center)
Research Interest
Functional proteomics approaches to the definition of protein-protein interaction networks, the identification of enzyme-substrate and drug-protein target interactions at a proteome-wide scale, and screening for antibody-like affinity molecules for biomarkers using in vitro protein selection technology.
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bryan_roth@med.unc.edu Professor (joint appointment with Department of Pharmacology) Director, NIMH Psychoactive Drug Screening Program
Research Interest
G-protein coupled receptors structure and function ranging from the
atomic-level analysis of ligand-receptor interactions to in vivo
studies.
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sfs@email.unc.edu Associate Professor
Research Interest
Bio-organic and biophysical chemical investigations of the mechanisms of DNA repair, directed evolution of novel enzymes, and development of alternate strategies for targeting drug-resistant pathogenic microorganisms.
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qszhang@unc.edu Assistant Professor
Research Interest
Studying endogenous, small molecule-protein interactions and their downstream signaling.
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Joint Appointments

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crimmins@email.unc.edu Distinguished Professor and Chair, Department of Chemistry Professor, School of Pharmacy, Division of MCNP (joint appointment)
Research Interest
Development of new synthetic methods, novel synthetic strategies and
total synthesis of biologically active and structurally interesting
natural products.
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khahn@med.unc.edu Distinguished Professor, Department of Pharmacology Professor, School of Pharmacy, Division of MCNP (joint appointment)
Research Interest
New tools for imaging and precise manipulation of protein activity
within living cells and animals; spatio-temporal dynamics of signaling
networks: Adhesion, Rho family and MAPK signaling
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Research Faculty

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svfrye@email.unc.edu Research Professor Director, Center for Integrative Chemical Biology and Drug Discovery
Research Interest
Drug design, enzyme inhibitor design, protein kinases
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Adjunct Faculty
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Arnold Brossi
Adjunct Professor
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Edward Garvey, PhD
epgarvey@mindspring.com Adjunct Professor, School of Pharmacy Section head, biochemistry department, GlaxoSmithKline
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Vijay Gombar, PhD
vjgombar@nc.rr.com Adjunct Professor, School of Pharmacy Senior Research Investigator, GlaxoSmithKline
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Connie Vance, PhD
cvance@endacea.nctda.org Adjunct Assistant Professor, School of Pharmacy Senior Research Scientist, Endacea, Inc.
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Chris Waller, PhD
chris.waller@pfizer.com Adjunct Associate Professor, School of Pharmacy Associate Director, (Discovery) Research Informatics, Pfizer, Inc.
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Stan Young, PhD
young@niss.org Adjunct Professor, School of Pharmacy Assistant Director for Bioinformatics, National Institute of Statistical Sciences
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Primary Faculty Research Faculty Adjunct Faculty
Faculty Spotlight
Read more about Andrew Lee, an expert in NMR spectroscopy
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